Yeah 4-1's are generally much easier to manufacture and not screw up...which makes them cheaper, and less likely to be hand made...4-2-1's are generally hand made and much more tedious to be made properly, thus more expensive...
Case in point, even the mild steel AWR header is hand made and is over $400, or used to be...
but regardless Andy hit it...4-2-1's help with entire rev range usually by eliminating pumping losses, as well as help with high end scavaging...While most 4-1's simply give a broader powerband up high, and can sometimes hurt lowend slightly...depending on the pipe merging and ID's...
but all that is somewhat meaningless with the available headers for the FS...all give noticable gains, within a few whp of each other...and the OBX 4-1 is much cheaper, and hasn't shown any lowend losses, with almost all of the AWR's mid range and high end performance...But ithe OBX is nickel plated steel, rather than full stainless...and the AWR is hand made (which is not necessarily a better thing, there have been some quality problems in the past from them)...its a price matter really...the AWR is almost double the price of the OBX...and will most likely last longer, with better welds and the fact that it is full stainless...for racing purposes, it is also a better candidate for heat wrapping, which wouldn't be a great idea on coated steel...But don't feel like downgrading to only an OBX will leave you with a ton less hp...that is not the case for mild modding on an NA protege...