Very easily. The CX-5 can handle up to 8 bluetooth phones.
The setup is split into music and phone, so you can actually choose to have one on phone while other plays music. My wife and I share the car a lot, and changing between the two is easy.
If you need additional music devices, you can also plug in an iPod/iPhone or another into the AUX jack. You can play between all of them easily with very few changes to settings.