If you have a race motor, you want to run the highest possible comp ratio and highest octane gas. Higher comp motors make more power per psi of boost. The knock threshold of higher comp ratio motors is what holds people back when they use pump gas, so they resort to lowering the comp ratio to run more boost. Lower comp will give you more room when tuning for more boost, but too low a comp (less than 8.5), you will have to run a lot of boost to make up for it.
If I wanted to make 300-350hp. 9:0 @ 18 psi or 8.5:1 @ 25 psi. Which would I do? The 9:0 because it is more efficient. The powerband on the 9:0 will come on sooner in the low end and will have less stress as it is running less boost.
You'll need more than just rods and pistons to make high hp. Rods and pistons alone, do not make power. They are heavier than stock and will rob power due to the added weight in the reciprocating assembly or if you go lower compression you will lose power. If you gain any power, it'll be due to improved ring sealing and from balancing the assembly. Besides a larger turbo, headwork will free up a lot of HP. A set of turbo grind cams will produce big midrange to top end power. Then you will need a standalone to tune the whole thing, along with the correct size fuel injectors.
A lot of you guys say you want big power, but many of you forget the tranny doesn't hold big power. Are you prepared to spend $2000 and up on beefed up transmission parts after you dropped around $5000 in engine parts and labor?