I considered the Dueler 422 Ecopias but the OE Dueler 400s didn't make it 30k miles. I researched all of my options extensively and ultimately chose the Yokohama YK580 instead. The Dueler 422s would have been $1,078.42 OTD and the YK580s were only $862.18 OTD (at Discount Tire).
Even though the Yokos were very affordable, I didn't choose them just because of the price. They are considered a Low Rolling Resistance tire, but they don't sacrifice any handling or traction like most LRRs. They are also quieter on the highway and the ride quality isn't quite as stiff/harsh as it was before.
Yokohama reduces rolling resistance in a very unique way and unlike any other manufacturer. A significant percentage of petroleum oil traditionally used in the tire manufacturing process is replaced with Orange Oil (as in the citrus fruit)! In doing so, they have managed to create LRR tires without sacrificing performance, comfort or quality.
I've put almost 4,000 miles on mine so far and my average fuel economy has increased by about 0.7mpg so far. It doesn't sound like a huge improvement, but considering that my average was 16.8mpg overall, I'll take any imrprovement I can get! I have noticed that they seem to improve highway mileage more than city/mixed driving. I just drove 400 miles round trip to visit family in South Carolina and I've never managed to keep it above 20mpg for the entire trip before. This time, I got 20.9mpg going 75-80mpg with the A/C on and I had to make a few 'aggressive' passes to get around idiots blocking the left lane coming back down I-85! So I wasn't trying to improve my mileage, but I did anyway! =)