i use that size tire without any rubbing in the back unless you have two 200+ pound people in the back seat but is still not a big deal unless you hit a huge bump. in the front it rubs a tiny bit on the inside of the fender well if you do a tight turn. no big deal either way and looks so much more aggressive. if you are lowered at all i would reconsider though.
thats all ive ever run. when i rotated my tires last i noticed a very minimal amount of wear. just take bumps slower with people in the backseat just like speedin said.